At Magen Biotech, we have dedicated over a decade to advancing the field of biological sample preparation. Our expertise encompasses sample collection and preservation, nucleic acid purification, and automation, with a product lineup exceeding 500 items. We aim to provide high-quality products and solutions to clinical users, scientific researchers, biological companies, agricultural applications, and government departments. Among our extensive range of products, guanidine hydrochloride plays a critical role in the nucleic acid extraction process.
Understanding Guanidine Hydrochloride
Guanidine hydrochloride is an essential reagent in our nucleic acid extraction kits, recognized for its powerful denaturing and ionizing properties. This compound promotes the solubility of hydrophobic molecules and denatures proteins, making it an effective denaturant and inactivator of various enzymes and proteins. In a 6 M guanidine hydrochloride solution, the ordered secondary structure of almost all proteins is disrupted, leading to the extension of peptide chains and alteration of tertiary structures. This feature is crucial in nucleic acid extraction, where guanidine hydrochloride serves as a cleaning solution (> 3M), binding solution (4-6M) for protein removal, and lysate for genomic DNA and total RNA extraction.
Applications of Guanidine Hydrochloride in Nucleic Acid Extraction
Our guanidine hydrochloride product is carefully screened and quality-controlled to ensure optimal performance in nucleic acid extraction. It is used extensively in various stages of the extraction process, enhancing the efficiency and yield of nucleic acids. Unlike guanidine isothiocyanate, guanidine hydrochloride exhibits low absorbance at A260, A280, and A230, resulting in a more ideal A260/230 ratio for nucleic acid products. This makes it a preferred choice in our HiPure and MagPure series kits.
Why Choose Magen Biotech for Guanidine Hydrochloride
At Magen Biotech, we ensure that all our products, including guanidine hydrochloride, meet the highest standards of quality and performance. Our guanidine hydrochloride is ideal for plasmid extraction, lysis solutions, and cleaning solutions. By choosing our products, researchers and clinicians can achieve reliable and reproducible results in their nucleic acid extraction processes.
Key Features of Guanidine Hydrochloride from Magen Biotech
- High Purity: Our guanidine hydrochloride has a purity level of 99.5%, ensuring minimal impurities in your extraction process.
- Consistency: We maintain strict quality control measures to ensure consistent product performance.
- Optimized for Molecular Biology: Specially formulated for molecular biology applications, our guanidine hydrochloride is ideal for a wide range of nucleic acid extraction needs.
Conclusion
In summary, guanidine hydrochloride is a vital component in our nucleic acid purification kits, playing a crucial role in protein denaturation and nucleic acid extraction. At Magen Biotech, we are committed to providing high-quality guanidine hydrochloride that meets the stringent requirements of scientific research and clinical applications. For more information or to place an order, please contact us at info@magen-tec.com.
Explore our range of products and discover how Magen Biotech can enhance your research with our reliable and efficient nucleic acid extraction solutions.