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Magen Biotech and Micro Filtration: Enhancing Sample Preparation Efficiency

Release date:2024-05-31

At Magen Biotech, we have dedicated over a decade to perfecting the art of biological sample preparation. Our expertise encompasses a wide array of services including sample collection and preservation, nucleic acid purification, and automation. One of our standout products is the HiPure DNA Micro Column. Designed with high-quality glass fiber filter membranes, this product epitomizes our commitment to quality and innovation in the field of micro filtration.

The Importance of Micro Filtration in Nucleic Acid Purification

Micro filtration is a critical process in nucleic acid purification, ensuring the removal of contaminants and the isolation of high-purity DNA and RNA. At Magen Biotech, our HiPure DNA Micro Column leverages advanced micro filtration techniques to provide researchers and clinical users with reliable and efficient tools for their work. Our columns are built to maintain long-term stability and high binding capacity, which are essential for consistent experimental results.

Features of the HiPure DNA Micro Column

The HiPure DNA Micro Column is a testament to our rigorous quality control and innovative design. Here are some of its key features:

- High-Quality Materials: Our columns are made using premium glass fiber filter membranes (GF/B, GF/D, GF/F), ensuring superior performance and durability.
- Long-Term Stability: Our nucleic acid adsorption columns remain stable and maintain their binding capacity for up to four years at room temperature.
- High Binding Capacity: The columns offer a maximum binding yield of up to 50 μg in alcohol-mediated binding processes, making them ideal for a variety of applications.

The Adsorption Mechanism

The HiPure DNA Micro Column operates on a principle based on the affinity between negatively charged DNA and positively charged glass fibers. In high salt and ethanol solutions, DNA/RNA binds to the glass fiber, interacting with the hydrophilic matrix on silica through hydrogen bonds. This tight binding ensures that all contaminants are effectively removed by the washing solution. At high salt concentrations, nucleic acids selectively bind to the silica gel membrane, while other pollutants, mainly proteins, are washed away.

Applications of Magen Biotech Products

Magen Biotech’s products, including the HiPure DNA Micro Column, have versatile applications across various fields:

1. Forensic Analysis: Our micro filtration technology is crucial in isolating DNA for forensic investigations.

2. Cancer and NIPT: Our circulating DNA kits and FFPE kits play a significant role in cancer research and non-invasive prenatal testing.

3. Genetic Screening: Various blood and tissue kits cater to comprehensive genetic screening requirements.

Conclusion

At Magen Biotech, our commitment to quality and innovation is evident in our wide range of products designed to enhance biological sample preparation. Our focus on micro filtration ensures that our products meet the highest standards of performance and reliability. Whether for clinical applications, scientific research, or environmental testing, Magen Biotech provides the tools necessary for accurate and efficient nucleic acid purification.

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