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Unlocking the Potential of 6M Guanidine Hydrochloride in Nucleic Acid Extraction

Release date:2024-02-22

In the field of nucleic acid extraction, Magen Biotech's 6M Guanidine Hydrochloride stands as a game-changer. Extracting high-quality nucleic acids is of paramount importance in various industries, and the right tools can make all the difference.


Understanding Guanidine Hydrochloride

Properties and Characteristics

Magen Biotech's 6M Guanidine Hydrochloride boasts exceptional properties and characteristics. As a powerful denaturantor ionizing agent, it enhances the solubility of hydrophobic molecules and facilitates the denaturation of proteins. Moreover, it effectively denatures and inactivates a wide range of enzymes and proteins, altering their secondary and tertiary structures.

Applications of 6M Guanidine Hydrochloride

Protein Removal in Nucleic Acid Extraction Process

When it comes to nucleic acid extraction, 6M Guanidine Hydrochloride plays a pivotal role in protein removal. It serves as a cleaning solution (> 3M) and binding solution (4-6M), ensuring the elimination of unwanted proteins. This critical step provides a clean foundation for subsequent processes.

Specific Use in Plasmid Extraction

The exceptional capabilities of Magen Biotech's Guanidine Hydrochloride also shine in plasmid extraction. With precise application, it aids in the successful extraction of plasmids, essential in various genetic engineering and molecular biology applications.

Lysis Solution for Genomic DNA and Total RNA Extraction

Magen Biotech's Guanidine Hydrochloride serves as an effective lysis solution, enabling the extraction of genomic DNA and total RNA. This vital process requires a reliable and efficient solution, and Guanidine Hydrochloride fulfills that role with its ability to disrupt protein structures and facilitate nucleic acid release.

Advantages of Magen Biotech's Guanidine Hydrochloride

Low Absorbance and Ideal A260/A230 Ratio

One of the standout advantages of Magen Biotech's Guanidine Hydrochloride is its low absorbance in A260, A280, and A230 measurements. This characteristic ensures accurate readings and precise quantification of nucleic acids. Additionally, the product offers an ideal A260/A230 ratio, further enhancing the quality of the nucleic acid product.

Recommended Transportation and Preservation Conditions

Magen Biotech recommends storing the 6M Guanidine Hydrochloride at room temperature, in a dry and dark environment. These optimal preservation conditions ensure the longevity and integrity of the product, allowing for consistent performance.

Conclusion

In summary, Magen Biotech's 6M Guanidine Hydrochloride plays a vital role in nucleic acid extraction. Its properties as a denaturantor ionizing agent, along with its varied applications, make it an indispensable tool for protein removal, plasmid extraction, and genomic DNA and total RNA extraction. With its low absorbance and ideal A260/A230 ratio, Magen Biotech's Guanidine Hydrochloride sets a new standard of excellence in nucleic acid extraction. By choosing high-quality products like this, researchers and professionals can ensure accurate and reliable results, driving advancements in their respective fields.


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