At Magen Biotech, we take pride in our commitment to providing our customers with the highest quality raw materials for their scientific and industrial needs. One of our core products is Guanidine hydrochloride, a powerful denaturant and ionizing agent that plays a crucial role in the field of nucleic acid extraction.
The Importance of Guanidine Hydrochloride in Nucleic Acid Extraction
Guanidine Hydrochloride is a fundamental component in the process of nucleic acid extraction, serving as a cleaning solution, binding solution, and lysate for genomic DNA and total RNA extraction. Unlike its counterpart, Guanidine Isothiocyanate, Magen Biotech's Guanidine Hydrochloride has low absorbance in A260, A280, and A230, resulting in a more ideal ratio of nucleic acid product A260/230.
Magen Biotech's Commitment to Quality
At Magen Biotech, we understand that the quality of our Guanidine Hydrochloride is paramount to the success of our customers' projects. That's why we have implemented strict quality control measures to ensure that our product meets the highest standards.
Purity of Saturated Solution (8M)
The 8M mother liquor of Magen Biotech's Guanidine Hydrochloride is heated and dissolved. After dissolution, the insoluble matter is filtered with 3 layers of rapid filter paper, ensuring a high level of purity.
pH Value (6M)
Magen Biotech's Guanidine Hydrochloride has a pH value of 5.0-5.5 when in a 6M solution, further demonstrating our commitment to quality and consistency.
Applications of Guanidine Hydrochloride
The molecule known as guanidine hydrochloride is extremely versatile and can be used for a wide variety of purposes. In addition to its application in the process of extracting nucleic acids, it is also a potent denaturant or ionizing agent that has the ability to increase the solubility of hydrophobic compounds and denature proteins. In addition to this, it is an efficient denaturant and inactivator of a wide range of enzymes and proteins.
In a 6M Guanidine Hydrochloride solution, the ordered "secondary structure" (maintained by intermolecular non-covalent interactions, such as hydrogen bonds and hydrophobic bonds) of almost all proteins is destroyed, and the peptide chain is stretched, changing the tertiary structure.
Conclusion
At Magen Biotech, we are dedicated to providing our customers with the highest quality Guanidine Hydrochloride and exceptional customer service. Our team of experts is committed to understanding your unique needs and working with you to ensure that you receive the best possible product and support. Whether you are working in the field of nucleic acid extraction, protein research, or any other application that requires Guanidine Hydrochloride, Magen Biotech is your trusted partner. Contact us today to learn more about our products and how we can help you achieve your goals.