At Magen Biotech, we have dedicated over a decade to enhancing biological sample preparation, earning our place among the top biotech companies. Our extensive product line includes solutions for sample collection and preservation, nucleic acid purification, and automation. With more than 500 different products, we aim to deliver high-quality products and solutions to clinical users, scientific researchers, biotechnology companies, agricultural applications, and government departments.
Understanding Cell Free DNA
Cell free DNA (cfDNA) refers to DNA fragments that are freely circulating in the bloodstream. These fragments can originate from various sources, including tumor cells, fetal cells, and apoptotic or necrotic cells. Typically found as short fragments (<1000bp), cfDNA is present in serum or plasma and holds significant potential for non-invasive diagnostic applications. Our HiPure Circulating DNA Midi Kit C is designed to efficiently purify these circulating nucleic acids, facilitating downstream applications such as qPCR, liquid or solid chip analysis, hybridization, and SNP detection.
Key Features of HiPure Circulating DNA Midi Kit C
Our HiPure Circulating DNA Midi Kit C (Catalog No. D3182C) is tailored to meet the needs of researchers working with cfDNA. This kit employs silica technology and a mini spin column for manual (vacuum) processing, ensuring high-purity DNA extraction from serum, plasma, and other cell-free fluid samples. The kit is available in two sizes: 10 preps for $136.00 and 50 preps for $547.00, offering flexibility for different research scales.
The main functions of the HiPure Circulating DNA Midi Kit C include:
- Efficient isolation of circulating DNA from 1-5ml of plasma, serum, or body fluids.
- Applicability in various molecular biology techniques, including qPCR and SNP detection.
Applications and Benefits
The HiPure Circulating DNA Midi Kit C is highly versatile and can be used in a range of applications:
- Non-invasive prenatal testing (NIPT): Detect fetal DNA in maternal blood.
- Oncology research: Identify tumor-specific extracellular DNA fragments.
- Genetic screening: Analyze genetic material from blood samples without invasive procedures.
- Infectious disease detection: Extract viral DNA/RNA for pathogen identification.
Using this kit, researchers can achieve reliable and reproducible results, which are crucial for advancing clinical diagnostics and biomedical research.
Conclusion
At Magen Biotech, we are committed to advancing the field of biological sample preparation with our innovative products. The HiPure Circulating DNA Midi Kit C is a testament to our dedication to quality and efficiency in isolating circulating free DNA. Whether you are working in clinical diagnostics, cancer research, or genetic screening, our kit provides a robust solution for your cfDNA purification needs.